Bremelanotide

Also known as: PT-141 generic, Vyleesi generic

HormonalFDA APPROVED

Clinical Status

FDA Approved — HSDD in premenopausal women (marketed as Vyleesi).

Mechanism of Action

A cyclic heptapeptide melanocortin receptor agonist. Activates MC4R and MC1R in the central nervous system, stimulating sexual arousal pathways independently of peripheral vascular mechanisms.

Dosing Defaults

Dose

1.75 mg

Frequency

As needed (max 1 dose per 24h)

Administration

Subcutaneous injection

Timing

45 minutes before anticipated activity

Food

with or without

Duration

As needed

Dose range: 0.5-2 mg per dose

Peak effect occurs 45-60 minutes post-injection.

Side Effects

•Nausea (40%)
•Flushing (20%)
•Headache
•Injection site reactions
•Transient hypertension
•Skin darkening with repeated use

Contraindications & Warnings

⚠Uncontrolled hypertension
⚠Cardiovascular disease

•Not medical advice
•Maximum 8 doses per month recommended

Compare

Compare Bremelanotide with another peptide side-by-side.

Calculate Dose

Use the reconstitution calculator to prepare your Bremelanotide dose.

Open Calculator

Related Hormonal Peptides

PT-141

FDA APPROVED

Hormonal

FDA-approved for hypoactive sexual desire disorder. Works via brain pathways.

Melanotan II

PRECLINICAL

Hormonal

Tanning and sexual function peptide. Significant safety concerns.

Kisspeptin

PHASE 2

Hormonal

Master regulator of reproductive hormones. Triggers natural GnRH release.

Oxytocin

FDA APPROVED

Hormonal

The "bonding hormone." FDA-approved for labor induction.

This information is for educational purposes only and is not medical advice. Dosing data is based on research literature and community reports. Always consult a qualified healthcare provider before using any peptide.