Acetyl Hexapeptide-3
Also known as: Argireline, AH3
Clinical Status
Cosmetic use — widely available globally.
Mechanism of Action
Inhibits SNARE complex assembly required for vesicle docking and neurotransmitter release. Reduces the depth of expression wrinkles by limiting repetitive muscle contractions.
Dosing Defaults
Dose
Topical
Frequency
2x daily
Administration
Topical (serums, creams)
Timing
Morning and evening
Food
with or without
Duration
Ongoing use
Dose range: Topical application (5-10%)
Regular application maintains wrinkle-relaxing effects.
Side Effects
- •Mild tingling
- •Redness (rare)
Contraindications & Warnings
- •Not medical advice
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This information is for educational purposes only and is not medical advice. Dosing data is based on research literature and community reports. Always consult a qualified healthcare provider before using any peptide.