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Acetyl Hexapeptide-3

Also known as: Argireline, AH3

Skin & HairPHASE 2

Clinical Status

Cosmetic use — widely available globally.

Mechanism of Action

Inhibits SNARE complex assembly required for vesicle docking and neurotransmitter release. Reduces the depth of expression wrinkles by limiting repetitive muscle contractions.

Dosing Defaults

Dose

Topical

Frequency

2x daily

Administration

Topical (serums, creams)

Timing

Morning and evening

Food

with or without

Duration

Ongoing use

Dose range: Topical application (5-10%)

Regular application maintains wrinkle-relaxing effects.

Side Effects

  • Mild tingling
  • Redness (rare)

Contraindications & Warnings

  • Not medical advice

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This information is for educational purposes only and is not medical advice. Dosing data is based on research literature and community reports. Always consult a qualified healthcare provider before using any peptide.